A retrospective analysis was performed on 5,380 eyes for the rate of cystoid macular edema development following uncomplicated Phacoemulsification with four different therapeutic regimens: postoperative generic ketorolac 0.4% and prednisolone 1%, postoperative name-brand ketorolac 0.45% and prednisolone 1%, postoperative bromfenac 0.09% and prednisolone 1%, preoperative and postoperative bromfenac 0.09% alone.
Topical non-steroidal anti-inflammatory drugs lower the risk of post-cataract surgery cystoid macular edema compared to other therapies evaluated.
Postoperative generic ketorolac 0.45% and prednisolone 1% demonstrated the highest rate of cystoid macular edema development.
Bromfenac without corticosteroids demonstrated lower rates of cystoid macular edema compared to other combinations of nonsteroidal anti-inflammatory drugs with corticosteroids.
Adapted from: Walter KA, Lee RY, Chen K, Komanski C. Incidence of cystoid macular edema following routine cataract surgery using NSAIDs alone or with corticosteroids. Arq Bras Oftalmol. 2020;83(1):55-61
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